We are seeking a motivated and skilled scientist to lead and support
organ chip research projects focused on modeling neurodevelopment and
evaluating the effects of nutritional components. The ideal candidate will have
a strong background in developmental neuroscience, organoid culture, and
microphysiological systems.

Key Responsibilities:

• Independently
  design and execute organoid/organ chip-based research projects related to
  brain development, including modeling of neuronal, glial, and blood-brain
  barrier (BBB) compartments.


• Develop and
  optimize protocols for the differentiation and co-culture of iPSC-derived
  neurons, microglia, astrocytes, and/or BBB components.


• Establish 3D
  neurodevelopmental models and evaluate the impact of nutritional compounds
  (e.g., DHA, HMOs, prebiotics, micronutrients) on neuronal maturation,
  synaptogenesis, inflammation, and functional connectivity.


• Implement
  cellular, molecular, and functional assays (e.g., immunostaining, qPCR,
  cytokine profiling, calcium imaging, multi-electrode array recording) to
  assess organoid responses to nutritional interventions.


• Contribute to
  the development of a functional screening platform for evaluating the
  efficacy of bioactive nutritional components.


• Coordinate
  project progress, ensure high-quality data collection and analysis, and
  participate in manuscript and report writing in both Chinese and English.

Preferred Qualifications:

• PhD or
  equivalent in Neuroscience, Developmental Biology, Biomedical Engineering,
  or related fields.


• Experience with
  human iPSC culture and neural differentiation is essential.


• Familiarity
  with organ-on-a-chip systems or advanced 3D culture models.


• Knowledge of
  nutritional neuroscience, gut-brain axis, or neuroinflammation is a strong
  plus.


• Proven ability
  to manage and execute multidisciplinary research projects.


• Excellent
  communication skills and scientific writing ability in both English and
  Chinese.

岗位描述：神经科学方向科研人员——用于营养神经发育研究的类器官/器官芯片模型

我们正在招聘一位积极进取、具备扎实科研能力的科研人员，主导和参与器官芯片相关研究项目，重点聚焦于神经发育模型的构建及营养成分对其影响的机制研究。理想候选人应具备神经发育、生物工程或类器官培养等相关背景。

岗位职责：

• 独立设计并执行基于类器官/器官芯片的神经发育相关研究项目，包括神经元、胶质细胞和血脑屏障等模块的建模；


• 建立并优化人源iPSC分化为神经元、小胶质细胞、星形胶质细胞及血脑屏障等细胞类型的培养和共培养体系；


• 构建三维神经发育模型，系统评估营养成分（如DHA、人乳低聚糖、益生元、微量元素等）对神经发育过程中的成熟、突触形成、炎症反应及功能连接的影响；


• 应用细胞与分子生物学方法（如免疫染色、qPCR、细胞因子分析、钙成像、多电极阵列记录等）评估类器官对营养干预的反应；


• 参与营养功能成分的筛选平台开发，推动其在功能验证中的应用；


• 协调项目进展，确保高质量数据收集与分析，撰写项目报告与中英文科研论文。

任职要求：

• 拥有神经科学、发育生物学、生物医学工程或相关专业的博士学位；


• 具有人源iPSC培养及神经分化经验；


• 熟悉类器官/器官芯片系统或先进三维培养技术；


• 具有营养神经科学、肠-脑轴或神经炎症研究经验者优先；


• 具备良好的项目管理和跨学科协作能力；


• 具备优秀的中英文沟通能力和科研写作能力。