职位详情
下游纯化工艺开发研究员
1.5-2万·14薪
南京普洛齐企业管理咨询有限公司
广州
不限
硕士
04-30
工作地址

百济神州广州生物岛创新中心

职位描述
Participate in the purification method development of antibodies and protein drugs, including buffer screening, resin screening, method optimization of different chromatography techniques (affinity, ion exchange, hydrophobic interaction and Gel Filtration) and ultrafiltration.
参与抗体和蛋白药物的纯化方法开发,包括缓冲液筛选、填料筛选、不同层析技术方法优化(亲和、离子交换、疏水相互作用和凝胶过滤)和超滤。
Perform simple characterization of purified products, such as SDS-PAGE, protein concentration, SEC-HPLC, endotoxin test etc.
对纯化产物进行简单分析,例如蛋白浓度测定、 SDS-PAGE、SEC-HPLC 、内毒素检测等。
Good communication and close cooperation with upstream, analysis and formulation colleagues to ensure the smooth development of team work.
与上游,分析和制剂同事良好沟通紧密配合,保证团队工作开展。
Ensures the integrity and authenticity of experiment records and the reliability of data.
确保试验记录真实完整,实验数据科学可靠。
Independently operates, troubleshoots, and maintains purification equipment.
独立操作和维护相关的纯化仪器设备,并解决常见问题。
Ensures that experimental operations and related activities comply with SOP and EHS requirements.
确保与试验有关的活动符合相关SOP和EHS要求。
Requirements:
Familiarity with various chromatography principles, the properties of resins, and the operation of AKTA purification equipment.
熟悉各种层析原理、介质填料的性质以及AKTA纯化设备的具体操作。
Able to independently complete the design and implementation of protein purification process development, process optimization, and process scale-up.
能独立完成蛋白纯化工艺开发、工艺优化、工艺放大的方案设计并实施。
Strong organization and coordination skills, good team spirit, strong analytical and problem-solving skills.
有较强的组织协调能力、良好的团队精神、较强的分析和解决问题的能力
Strong learning ability, willing to explore new technology, proactive to search solutions or look for support when facing challenges at daily work.
有较强的学习能力、积极主动地学习新技术,工作中遇到挑战时能主动寻找方案或寻求帮助。
Fluent in English.
英语熟练。
Education Required:
Master’s degree in engineering, Chemistry, Biology, Biotechnology or related field;
工程、化学、生物、生物技术等相关专业硕士学位;
with 3 years of work experience in purification.
有3年的纯化工作经验。

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