岗位简介

Job description:

您将从事寡核苷酸新药的研发工作，负责完成从毫克级到克级的合成批量任务。工作中，您将运用先进的合成系统制备各类复杂寡核苷酸，并与经验丰富的分析、纯化研究员紧密协作，以获得高纯度产物。此外，您还将有机会与跨国药企的药物化学专家进行面对面交流学习。

Youwill be responsible for the synthesis of oligonucleotides in mg to gram scale. In this role, you will have opportunities to use the most advanced automatic synthesis system to prepare various complex oligonucleotides and work with experienced analysis and purification researchers to obtain oligonucleotides with high purity. You will communicate with the experts from multinational pharmaceutical companies face to face.

工作职责

Responsibilities

1、学习使用不同的自动合成仪以及优化参数。

2、设计寡核苷酸的合成路线。

3、对寡核苷酸合成的分析数据进行解析，并对合成方法进行适当的优化。

4、配合项目经理或副总定期向欧美客户定汇报课题进展情况；

5、及时地书写英文E-Note、日报和结题报告；

6、根据公司要求，及时地总结工作，上交实验数据资料。

1. Learns to operate different automatic synthesizer and to optimize parameters.

2.Proposes synthetic plan for different oligonucleotides.

3.Independently interprets analytical data of oligonucleotides synthesis, optimizes synthetic method properly.

4.Regularly cooperates with project managers or VPs to report project progress to domestic or foreign clients.

5.Timely and accurately records English E-Note, prepares daily reports and final reports.

6.Timely summarizes and submits the experimental data according to company policies.

任职要求

Qualifications:

1、有机化学或药物化学相关专业博士学历，研究方向为寡核苷酸；

2、具有较丰富的寡核苷酸合成经验；

3、较强抗压力，责任心强，具备团队合作精神，可带领一至多名实验助理开展研究工作；

4、优秀的英语听说读写能力。

1.Ph. D. degree in organic/medicinal chemistry with experience in oligonucleotides synthesis ;

2.Extensive experience in oligonucleotides synthesis;

3.Demonstrates ability to work under pressure, sense of responsibility and team collaboration, capably coaches one or more junior chemists;

4.Fluent in reading and writing in English; ability to effectively converse in English.