职位详情
博士研发员 Ph.D. Researcher
1.8-2.8万
武汉乐斯吉生物科技有限公司
武汉
不限
博士
09-17
工作地址

豹澥街道高新大道858号生物产业园二期B16-3楼

职位描述

加入我们创新的裂解酶研发团队


我们正在寻找一位积极进取、技术精湛的博士级科学家加入我们充满活力的团队。我们是一家在裂解酶领域拥有广泛国际影响力的领先公司,拥有多款一流的产品。


工作内容:


您将在研发新型裂解酶的过程中发挥关键作用,并将其用于治疗耐药细菌。您将加入我们世界领先的溶菌素研发平台,并在两位来自美国顶尖大学的博士科学家的指导下开展工作。


工作职责包括领导一个研发项目,以识别和验证针对特定目标生物体的靶分子。以下技能对于成功的候选人至关重要:


• 分子生物学:设计和执行涉及分子克隆的实验,包括质粒构建、PCR引物设计和测序结果分析。


• 微生物学:分离和操作菌株,尤其是苛性厌氧菌,严格遵守无菌操作规程,并进行MIC测试、生物膜研究以及厌氧操作台的使用等实验。


• 实验开发:具备高通量筛选和96/384孔板实验经验。具备机器人系统使用经验者优先!


• 蛋白质科学:运用多种生化技术纯化和表征重组蛋白。


• 数据管理:维护详细准确的实验数据记录,并及时向团队负责人提交报告。


我们寻求的人才:


• 独立且清晰的科学思维:能够开发、设计和开展创新研究。能够理解科学论文和专利。


• 团队合作:我们的研发团队是一个团结协作、广泛合作的团队。您必须能够有效地协作以实现您的目标。


• 教育背景:该职位要求博士学位。学科方向可为微生物学、生物技术或相关领域。


• 经验:虽然拥有行业经验者优先,但我们更看重拥有扎实基础知识和科研热情的候选人。我们非常重视之前与致病菌相关的工作经验。


• 技能:具备强大的分析和解决问题能力。能够设计和执行逻辑清晰、定义明确的实验。优秀的书面和口头沟通能力(大学英语六级或同等水平)。您需要能够用英语撰写报告。


• 加分项:具备在良好实验室规范 (GLP) 环境下工作的经验;动物模型(小鼠/大鼠)使用经验;熟悉不同的蛋白表达系统(例如,无细胞表达系统、酵母表达系统等);能够使用 Python 编程。


Join Our Innovative Endolysin Discovery Team


We’re
seeking a highly motivated and skilled PhD-level Scientist to join our dynamic
team. We are a leading company with large international footprint in the
endolysin field with several best-in-class products.


What You’ll Do:

You’llplay a crucial role in the discovery of novel endolysins for use as
therapeutics to solve the problem of drug-resistant bacteria. You will join our
world-leading endolysin discovery platform and work under the supervision of
two PhD scientists from a top-tier US university.


Responsibilities will include
leading a discovery project to identify and validate target molecules for
defined target organisms. The following techniques are important for a
successful candidate:

·
Molecular Biology: Designing and executing experiments involving molecular cloning – including plasmid construction, PCR primer design, and analysis of sequencing results.

·
Microbiology: Isolating and working with bacterial strains, especially fastidious anaerobic bacteria,
maintaining strict sterile techniques, and performing assays such as MIC
testing, biofilm studies, and utilizing an anaerobic hood.

· Assay Development: Experience with high throughput screening and 96/384-well plate assays. Experience with robotic systems is a plus!

· Protein Science: Purifying and characterizing recombinant proteins, utilizing a range of biochemical techniques.

· Data Management: Maintaining detailed and accurate records of experimental data and preparing timely reports for the team lead.


What We’re Looking For:

· Independence and clear scientific thinking: Ability to develop, design, and perform innovative research. Ability to understand scientific articles and patents.

· Team work: Our discovery team is a cohesive team that collaborates extensively. You must be able to collaborate effectively to achieve your goals.

· Education: PhD degree is an absolute requirement for this position. Subject could be in Microbiology, Biotechnology, or a related field.

· Experience: While prior industry experience is an advantage, we value candidates with strong foundational knowledge and a passion for research. We greatly value prior experience working with pathogenic bacteria.

· Skills: Strong analytical and problem-solving skills. Ability to design and execute logical and well-defined experiments. Excellent written
and verbal communication skills (CET-6 or equivalent proficiency in English).You will be expected to be able to write reports in English.

· Bonus Points: Experience working in a GLP environment; experience with animal models (mouse/rat);experience with different protein expression systems (for example, cell-free expression system, yeast expression system, etc.); ability to program in python.


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